EGFR Mutation PCR Detection Kit
LabTurbo™ EGFR Mutation PCR Test enables rapid, sensitive detection of clinically actionable EGFR mutations in non-small cell lung cancer (NSCLC), including major sensitizing and resistance variants across exons 18–21. Its targeted real-time PCR design delivers fast, reliable results to guide first-line EGFR-TKI selection and monitor acquired resistance. Suitable for both FFPE tissue and plasma cfDNA.
Key Features
Comprehensive EGFR Hotspot Coverage (Exons 18–21)
Detects 42 clinically actionable EGFR mutations, including common drivers (Exon 19 del, L858R), uncommon sensitizing variants, and key resistance markers.
Tissue + Plasma Sample Types
Supports FFPE tumor tissue for baseline genotyping and plasma cfDNA (liquid biopsy) for cases with limited tissue and for follow-up monitoring.
High Sensitivity for Low-Frequency Mutations
Optimized real-time PCR chemistry enables reliable detection of low allele fractions, making it suitable for ctDNA testing and early resistance signals.
Resistance Monitoring for 3rd-Gen TKIs
Includes T790M and C797S to detect resistance to osimertinib and other 3rd-generation EGFR-TKIs, helping clinicians adjust therapy faster.
Kit Components
- Primer/ Probe mixture (4 Mixes)
- PCR Master Mix (MM)
- EGFR Positive Control (PC EGFR)
- RNase-free water
Mutation Sites
- G719A
- G719S
- G719C
- S768I
- T790M
- C797S
- 2319_2320insCAC
- 2310_2311insGGT
- 2307_2308ins9GCCAGCGTG
- 2309_2310 AC>CCAGCGTGGAT
- 2311_2312ins9GCCGTGGACA
- L858R
- L858R
- L861Q